49ers TE George Kittle (hamstring) practiced all week and isn’t listed on the final injury report for Sunday’s game vs. the Packers. He should be ready for a full slate of snaps but downgrades to mid- to low-end TE1 status without QB Brock Purdy.
49ers QB Brock Purdy (shoulder) is out for Sunday's game vs. the Packers. His injured right shoulder evidently didn't progress throughout the week as the team had hoped. GM John Lynch said Friday that an MRI on the shoulder didn't show anything concerning, so we're not expecting this to be a long-term absence. But Purdy's absence this weekend leaves QB Brandon Allen as San Francisco's expected starter. Allen has been with the 'Niners since May 2023 but has not attempted a regular-season pass for them. He completed just 57% of his passes at 6.1 yards per attempt in limited action for the Broncos and Bengals from 2019-2022. Allen is clearly a significant downgrade for all San Francisco pass catchers. Expect the team to lean heavily on RB Christian McCaffrey on Sunday.
Commanders K Austin Seibert (hip) is listed as questionable for this weekend’s game vs. the Cowboys. He was a full-go in Friday’s practice, so we’re expecting him to play. Seibert is a nice fantasy option with Washington sporting a 27.75-point implied total.
Cowboys WR Brandin Cooks (knee) was limited in practice all week and is listed as questionable for Sunday’s game vs. the Commanders. We’ll see if Dallas activates him from IR for his first game since Week 4, but Cooks is not a recommended fantasy play in any format.
Cowboys TE Jake Ferguson (concussion) is out for Sunday’s game vs. the Commanders. That leaves Luke Schoonmaker as Dallas’ likely lead TE. He tallied 6 catches for 43 yards when Ferguson missed Week 2 and caught 6 of 10 targets last week after Ferguson exited in the first quarter. You could do worse if you’re desperate at TE this week.
Cowboys WR CeeDee Lamb (back, foot) is not listed on the final injury report for this weekend’s game vs. the Commanders. After sitting out on Thursday, he returned to a full practice on Thursday. We’re expecting him to play his usual role on Sunday. It hasn’t necessarily been pretty, but Lamb has totaled 22 targets and 14 catches with QB Cooper Rush over the last two weeks.
Lions TE Sam LaPorta (shoulder) put in a full week of practice and isn’t listed on the final injury report. He should be ready to play his usual role on Sunday against the Colts’ 30th-ranked TE defense.
Eagles WR DeVonta Smith (hamstring) is out for Sunday night’s game against the Rams after missing practice all week. He played through a hamstring issue in Week 11 but evidently had a setback at some point. Smith’s absence will mean more snaps for some combination of WRs Jahan Dotson, Johnny Wilson, and Ainias Smith. But targets figure to consolidate even more around WR A.J. Brown and TE Dallas Goedert.
Buccaneers WR Mike Evans (hamstring) is listed as questionable for this weekend’s game vs. the Giants. He was a full participant in Thursday’s practice but limited on Wednesday and Friday. We’re expecting Evans to play on Sunday, but it sounds like his snaps could be scaled back at least a little. “We’ll play him as long as he’s healthy and fresh and needs to be in there,” HC Todd Bowles said Friday. “But we’ll get him out when we have to.” Consider Evans a risk/reward WR2 in this plus matchup.
Raiders RBs Alexander Mattison (ankle) and Zamir White (quad) are listed as doubtful for Sunday’s game vs. the Broncos. Vegas will roll with Ameer Abdullah, Dylan Laube, and likely practice-squad callup Sincere McCormick in the backfield. We’re projecting Abdullah to lead in touches, but it’s a guess more than anything else. With the Raiders six-point underdogs with a 17.5-point implied total against a tough Denver defense, you should try to stay away from this backfield.
Vikings TE Josh Oliver (wrist, ankle) is out for Sunday’s game vs. the Bears. As crazy as it sounds, that might mean a bigger role for TE T.J. Hockenson. Oliver has run a pass route on about 50% of Vikings pass plays in both of the last two weeks, while Hockenson has been at 71% and then 57%.
Giants WR Darius Slayton (concussion) put in a full week of practice and is not listed on the final injury report for Sunday’s game vs. the Buccaneers. He’s just a desperation WR4 for now but would upgrade to WR3 status if WR Malik Nabers misses this game with his groin injury.
Giants WR Malik Nabers (groin) is listed as questionable for this weekend’s game vs. the Buccaneers. He was added to the injury report on Friday and did not practice. The Athletic’s Charlotte Carroll notes that Nabers said back in October that he’s been dealing with this groin issue since college. Nabers told ESPN’s Jordan Raanan on Friday that he expects to play on Sunday. We’ll look for further updates on the rookie’s status.
Bears WR Keenan Allen (ankle) is questionable for this weekend’s game vs. the Vikings. He was added to the injury report and limited in practice on Friday. We’ll look for further updates on Allen, but he was already an unexciting fantasy option before this news. His absence would boost the target potential for WR D.J. Moore, WR Rome Odunze, and TE Cole Kmet.
Bears RB D'Andre Swift (groin) is listed as questionable for this weekend’s game vs. the Vikings. He progressed from no practice on Wednesday to limited practice on Thursday to full participation on Friday. So Swift should play this weekend, but the groin adds risk to a guy who lost passing-down and goal-line work last week and has a negative matchup against Minnesota’s second-ranked RB defense.
Chiefs RB Isiah Pacheco (leg) won't play against the Panthers on Sunday. Pacheco has been back at practice for a couple of weeks now, but Kansas City will hold him out for at least one more game. That'll keep RB Kareem Hunt in a workhorse role in a dream spot with the Chiefs 10.5-point favorites against Carolina's 32nd-ranked RB defense.
Titans RB Tyjae Spears (concussion) is out for Sunday’s game vs. the Texans. That leaves the backfield to RB Tony Pollard, who has averaged 21.3 carries and 4.3 targets in three games without Spears earlier this season. Despite the difficult matchup, Pollard is a strong RB2 play this week.
Panthers K Eddy Pineiro (knee) is questionable for this weekend’s game vs. the Chiefs. He was added to the injury report on Thursday and did not practice on Friday. We’ll see if Carolina adds another kicker to the roster before Sunday, but you should stay far away from the situation in Week 12 fantasy lineups.
Panthers WR Adam Thielen (hamstring) was limited in practice all week and is listed as questionable for Sunday’s game vs. the Chiefs. HC Dave Canales said Friday, though, that Thielen will play. He’d be a desperation fantasy start against Kansas City’s 10th-ranked WR defense. WR Jalen Coker (quad) was added to the injury report and did not practice on Friday. He’s listed as questionable and should not be in Week 12 fantasy lineups.
Panthers RB Jonathon Brooks (knee) was a full-go in practice this week. He’s listed as questionable, but HC Dave Canales said Friday that Brooks is “absolutely” playing against the Chiefs this weekend. RB Miles Sanders (ankle) is out for that one, which clears the way for Brooks to be Carolina’s No. 2 RB. But we’re not expecting him to see a ton of volume behind Chuba Hubbard in his NFL debut. And the matchup is brutal against Kansas City’s top-ranked RB defense.
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