Cardinals TE Trey McBride (concussion) did not practice on Wednesday. He's looking unlikely to be cleared in time for this weekend's game vs. the Commanders. McBride's absence would leave Elijah Higgins as Arizona's likely lead pass-catching TE -- and push more targets to WRs Marvin Harrison, Michael Wilson, and Greg Dortch.
Eagles WRs A.J. Brown (hamstring) and DeVonta Smith (concussion) did not practice on Wednesday. Smith is unlikely to clear protocol in time for this weekend's game vs. the Bucs. And Brown looks no better than 50/50 to make it back for that one. If both guys are out, Philadelphia would be down to WRs Jahan Dotson and Johnny Wilson on the active roster. WR Parris Campbell was elevated from the practice squad for last week's game and would likely play again on Sunday. RB Saquon Barkley and TE Dallas Goedert would be the focal points of the offense.
Steelers RB Jaylen Warren (knee) did not practice on Wednesday. HC Mike Tomlin said earlier this week that he expected Warren to be limited today. We're tentatively projecting him to miss Sunday's game vs. the Colts. RB Najee Harris didn't practice on Wednesday but is listed with "rest." He'll be ready for this weekend's game and will be busy if Warren sits.
Texans WR Tank Dell (chest) did not practice on Wednesday. "Tank will be day-to-day,” HC DeMeco Ryans said. “We’ll see how he continues to progress.” It sounds like Dell still has a chance to play vs. the Jaguars this weekend, but we'll update his status again tomorrow.
Jaguars TE Evan Engram (hamstring) did not practice on Wednesday. HC Doug Pederson said Tuesday that he expected Engram to be "close" to being able to play vs. the Texans this weekend, but this isn't a good start. We'll see if Engram is able to get back on the field tomorrow.
Packers QB Jordan Love (knee) put in a limited practice on Wednesday. He was limited in all three practices last week before missing the Titans game, so this doesn't necessarily tell us anything. But Love seems to be trending toward returning for Sunday's game vs. the Vikings according to multiple reports. We'll keep you updated on his progress over the next few days.
Vikings QB Sam Darnold (knee) was a full participant in Wednesday's practice. It's confirmation that he'll be ready for this weekend's game vs. the Packers. Darnold ranks fifth among QBs in fantasy points and has finished top 14 at the position in all three weeks so far. He sits 12th in the Week 4 QB Rankings.
Vikings WR Jordan Addison (ankle) put in a limited practice on Wednesday. It was his first practice since going down in the opener and should put him on track to return for this weekend's game vs. the Packers. We'll keep tabs on Addison's progress over the next few days. He sits in low-end WR3 territory in the Week 4 Rankings.
Giants WR Darius Slayton (thumb) was limited in practice all week and is listed as questionable for Thursday night's game vs. the Cowboys. We're tentatively expecting Slayton to play. If he doesn't, Jalin Hyatt would step in as New York's No. 3 WR. This situation should only be impacting your DFS showdown lineups.
Broncos LB Alex Singleton suffered a torn left ACL in Sunday's win over the Buccaneers. HC Sean Payton had to confirm the injury after practice Wednesday because Singleton played through it for the rest of the game. The LB later reported soreness, and MRI confirmed the tear. He'll miss the rest of the season. Denver has Cody Barton, Justin Strnad, and Kristian Welch on the roster at non-edge LB. The Broncos also signed LBs Kwon Alexander and Zach Cunningham to the practice squad Wednesday. Barton is the best early bet to lead the group in playing time but is far from a sure thing to maintain that role the rest of the way.
Saints RB Alvin Kamara did not practice on Wednesday. He's dealing with a hip pointer and rib injury, HC Dennis Allen said. Kamara was able to play through the issues in the Week 3 loss to the Eagles but shouldn't be considered a lock to play vs. the Falcons on Sunday.
Commanders RB Austin Ekeler (concussion) is out for this weekend's game vs. the Cardinals, HC Dan Quinn said Wednesday. It's concerning that Ekeler was ruled out so early in the week. We'll see if he can clear concussion protocol in time for Week 5's game against the Browns.
Chargers HC Jim Harbaugh said Wednesday that an MRI on QB Justin Herbert's ankle revealed that the injury is "progressing." Herbert is out of his walking boot. It's still unclear whether he'll start this weekend's game against the Chiefs. Two things that might factor into that decision:
QB Taylor Heinicke would presumably get the start if Herbert misses the Chiefs game. We'll keep you updated on the situation.
Bears WR Keenan Allen (heel) put in a limited practice on Wednesday. "He's tracking to return this week if all goes well," NFL Network's Ian Rapoport tweeted.
Texans RB Joe Mixon is still "week to week" with his ankle injury, according to insider Aaron Wilson. It doesn't sound like Mixon is likely to play vs. the Jaguars on Sunday. Houston is expected to get RB Dameon Pierce back from his hamstring injury for that one, per Wilson.
The NFL has suspended Chargers S Derwin James one game for "repeated violations" of the safety rules. James was most recently flagged for an illegal hit in the loss to the Steelers. His seven such penalties since 2018 tie him for second-most in the NFL, but he has reached that number in fewer games than other "leaders" in the category. James appealed the suspension, but it was upheld. So he'll miss Sunday's game against the Chiefs. Elijah Molden looks likely to fill in.
The Chiefs elevated RB Kareem Hunt from the practice squad to the active roster. RB Keaontay Ingram was released in a corresponding move
Jaguars LB Foye Oluokun is "expected to miss several weeks" with plantar fasciitis, NFL Network's Tom Pelissero reports. We'll watch for further details on his expected return timeline, but this is an issue that tends to linger. Players often play through plantar fasciitis, including Chargers QB Justin Herbert earlier this season. That Oluokun is expected to miss time suggests a more serious case. Jacksonville will increase the roles of LB Ventrell Miller and Chad Muma in Oluokun's absence. We'll see exactly how playing time breaks down.
Panthers WR Adam Thielen suffered a hamstring injury during the Panthers' win against the Raiders. The team is placing him on injured reserve, meaning Thielen will miss at least the next four games, eligible to return for Week 8's contest against the Denver Broncos.
Jaguars LB Foye Oluokun left in the second quarter of Monday night's loss to the Bills with a foot injury. Initially listed as questionable to return, he was downgraded to out before the end of the game.
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