49ers RB Christian McCaffrey was limited in Thursday's practice and is listed on the injury report with calf and Achilles. HC Kyle Shanahan confirmed that the Achilles issue is not new (the team just wasn't required to disclose it until today's first official injury report).
Bengals WR Tee Higgins was added to the injury report on Thursday with a hamstring and limited in practice. The season couldn't officially start without Higgins hitting the injury report. He said afterward that he feels "amazing" and fully expects to play this weekend, but we'll see how he's listed on the final injury report on Friday afternoon. The Bengals are expected to have WR Ja'Marr Chase for Sunday's opener vs. the Patriots, although it's still unclear if he'll be ready for a full workload. The rest of the WR corps is rounded out by Andrei Iosivas, Trenton Irwin, Charlie Jones, and Jermaine Burton.
Packers TE Tucker Kraft (back) is listed as questionable for Friday night's game vs. the Eagles. He was added to the injury report on Wednesday and limited again in Thursday's practice. It's a new injury for Kraft, who missed time earlier in the offseason with a pectoral injury. Kraft shouldn't be in your Week 1 fantasy plans, but his absence would mean more playing time for TE Luke Musgrave.
Packers RBs MarShawn Lloyd (hamstring) and Emanuel Wilson (hip) are listed as questionable for Friday night's opener vs. the Eagles. Both guys got in limited practices on Wednesday and Thursday and figure to be active tomorrow. But neither is likely to play a big role. RB Josh Jacobs is a good bet to dominate touches against Philly. He sits 10th in the Week 1 RB Rankings.
Chargers RBs Gus Edwards and J.K. Dobbins are both going to get work, according to OC Greg Roman, but he plans to ride the hot hand if one of the RBs gets hot. With the Chargers running a more run-focused offense, whichever RB receives a majority of the carries could be in line for a solid day against the Raiders.
Steelers QB Russell Wilson was limited in Thursday's practice with the calf tightness that has been bothering him throughout training camp. HC Mike Tomlin confirmed that Wilson was limited, but would not comment on when they were informed of the tightness. Wilson will be further evaluated by the Steelers medical staff.
Chargers QB Justin Herbert says he expects he'll have to continue to manage the plantar fascia injury in his right foot that limited his time in training camp, according to Daniel Popper of The Athletic.
Asked about his plans for the backfield on Wednesday, Bucs HC Todd Bowles said it'll change on a "game-by-game basis" and be a "hot-hand" situation. Bowles also confirmed that RB Rachaad White will start Sunday's opener vs. the Commanders.
Rams WR Puka Nacua (knee) was a full participant in Wednesday's practice. He missed most of August after suffering a bursa sac injury to his knee. But the Rams never seemed worried about Nacua's Week 1 availability, and he's been back on the practice field since August 26. Today's full practice is final confirmation that Nacua will be ready for his usual role vs. the Lions on Sunday night. Get him into fantasy lineups.
Seahawks TE Noah Fant (toe) was limited in Wednesday's practice. Fant was sidelined for part of August with a previously undisclosed injury, which we now know is to his toe. The limited practice should put him on track to play vs. the Broncos on Sunday, but hopefully you have a more reliable option for your fantasy lineup this week.
Raiders TE Brock Bowers (foot) was limited in Wednesday's practice. The team has downplayed this issue, but it's been lingering for over two weeks now. The rookie seems on track to play vs. the Chargers on Sunday, but he'd be a more comfortable fantasy play with at least one full practice on Thursday or Friday.
Vikings WR Jordan Addison (ankle) was limited in Wednesday's practice. He's working back from an August 14 ankle injury and just returned to the field a couple of days ago.
Colts WR Josh Downs (ankle) did not practice on Wednesday. He's four weeks removed from suffering a high-ankle sprain and seems unlikely to be ready for Sunday's opener vs. the Texans. We'll continue to track Downs' status and see if he can make it back for Week 2.
Titans WR DeAndre Hopkins (knee) was limited in Wednesday's practice. He's expected to play in this weekend's opener vs. the Bears, but we're currently projecting his volume and efficiency to take a hit coming off the knee injury. We'll see what Hopkins does in practice the next two days and how he's listed on the final injury report.
Bills WR Curtis Samuel (toe) was a full participant in Wednesday's practice. He's on track to be available for this weekend's opener vs. the Cardinals -- and it seems like he'll be ready to play a full slate of snaps.
Steelers RB Jaylen Warren (hamstring) got in a limited practice on Wednesday. The fact that he was on the field at all puts him on track to be available for Sunday's opener vs. the Falcons. What he does over the next two days -- and how he's listed on the final injury report -- will give us a better idea of how much work he's in for. Warren sits lower than usual at 36th in the Week 1 RB Rankings.
Panthers RB Miles Sanders suffered a finger injury in Wednesday's practice, according to Steve Reed of The Associated Press. Carolina officially listed him as limited in the week's first practice report.
Bengals WR Ja'Marr Chase participated in the portion of Wednesday's practice open to the media. We'll see how he's listed on the official injury report later today, but this is obviously encouraging news in regards to Chase's status for Week 1 and beyond.
Falcons TE Kyle Pitts had a limited practice on Wednesday due to a hamstring injury per HC Raheem Morris. Per Morris, Pitts tweaked his hamstring a few weeks ago and has been practicing through it. There doesn't seem to be much worry about Pitts' availability on Sunday against the Steelers.
Eagles LB Devin White will not travel with the team for Friday's game against the Packers in Brazil. That marked a downgrade in his status after Philly listed White as a limited participant Tuesday. White's inactive status should leave Nakobe Dean and Zack Baun as the LB starters against Green Bay.
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