Colts RB Jonathan Taylor (ankle) remained sidelined for Wednesday's practice. "He’s working through it, he’s looking good," HC Shane Steichen said of JT. "We’ll see how the week goes for him, hopeful that he’ll be out there." Fantasy owners should not be counting on Taylor in Week 6 fantasy lineups. RB Trey Sermon (collarbone) also missed Wednesday's practice. No word on his status for Sunday's game vs. the Titans. If Taylor and Sermon are out, RB Tyler Goodson would be left as Indianapolis' starter.
Colts QB Anthony Richardson (oblique) remained limited in Wednesday's practice. He was limited all last week before missing the Jaguars game. Richardson's status for this weekend's game vs. the Titans remains uncertain. We'll track his progress over the next few days.
Eagles WRs A.J. Brown (hamstring) and DeVonta Smith (hamstring) were full participants in Wednesday's practice. They're both on track to return and play their usual roles vs. the Browns this weekend. Get them back into fantasy lineups.
Browns TE David Njoku (knee, ankle) did not practice on Wednesday. He returned from his high-ankle sprain last week and subsequently suffered a knee injury. Njoku doesn't seem particularly likely to play vs. the Eagles this weekend, but we'll track his status over the next few days.
Saints HC Dennis Allen said Wednesday that QB Spencer Rattler will start this weekend's game vs. the Bucs. The fifth-round rookie boasts exciting arm talent but completed just 53% of his passes at 5.3 yards per attempt this preseason. He's not a Week 6 fantasy option and is a downgrade for New Orleans' pass catchers. Allen also said Wednesday that QB Derek Carr (oblique) is "week to week" but won't go on IR.
Saints WR Rashid Shaheed (hip) did not practice on Wednesday. This could just be a rest day coming off the Monday nighter in Kansas City, but we'll update Shaheed's status again tomorrow. Assuming he plays vs. the Bucs this weekend, he'll be a shaky WR3 with QB Spencer Rattler at the controls.
Saints RB Alvin Kamara (hip, hand) did not practice on Wednesday. He seemed to make it out of Monday night's game vs. the Chiefs ok, so this is likely more of a rest day. We'll see if Kamara gets back on the field tomorrow.
Patriots RB Rhamondre Stevenson missed Wednesday's practice with a foot injury. He got banged up late in last week's loss to the Dolphins but said afterward that he expected to be fine for Week 6. We'll see if he gets back on the field tomorrow. Stevenson's absence against the Texans this weekend would mean a heavy workload for RB Antonio Gibson.
Texans RB Joe Mixon (ankle) remained sidelined for Wednesday's practice. HC Demeco Ryans labeled him "week to week" on Monday, so fantasy owners should not be expecting Mixon back for this weekend's game vs. the Patriots. RB Dameon Pierce (hamstring) was limited on Wednesday and is on track to return for Sunday's game. In that case, you should avoid Houston's backfield in Week 6 fantasy lineups.
Packers WR Christian Watson (ankle) returned to a limited practice on Wednesday. He seemingly has a shot to play vs. the Cardinals this weekend. Watson would be tough to trust in fantasy lineups in his first game back from what was reportedly a high-ankle sprain. But his return would take WR Dontayvion Wicks out of fantasy-lineup consideration.
Commanders RB Brian Robinson (knee) did not practice on Wednesday. He played through this injury last week, although he didn't record a touch in the second half. HC Dan Quinn said he was protecting his player in game that was never in question in the second half. Robinson figures to play vs. the Ravens on Sunday, but he likely won't be at 100%.
Jaguars TE Evan Engram (hamstring) remained limited in Wednesday's practice. He was limited all three days last week before missing the Colts game. HC Doug Pederson was optimistic about Engram's chances of playing vs. the Bears this weekend when asked on Wednesday, although he stopped short of guaranteeing that Engram will be out there. We'll keep tabs on his status over the next few days.
49ers K Jake Moody (ankle) is out for Thursday night's game vs. the Seahawks. Matthew Wright, who owns a career 85% FG conversion rate, will kick in Moody's place. With the Niners holding the week's third-highest implied total at 26.5 points, Wright is a fine replacement for Moody in fantasy lineups.
Colts WR Michael Pittman is expected to miss "multiple weeks" with a back injury, ESPN's Adam Schefter reports. Pittman didn't practice on Wednesday, so this injury presumably occurred in the Week 5 loss to the Jaguars. We'll look for more details on the injury and Pittman's timetable for return, but Schefter adds that, "injured reserve is an option."
Raiders HC Antonio Pierce named QB Aidan O'Connell the starter for this weekend's game vs. the Steelers. O'Connell has already seen action in place of QB Gardner Minshew twice this season, completing 19 of 32 passes (59%) for 176 yards (5.5 YPA), one TD, and one INT. He made 10 starts as a rookie last year, finishing with a 62% completion rate and 6.5 yards per attempt. O'Connell did have his three best games of the season over the final four weeks, ranking 14th among 39 qualifying QBs in Pro Football Focus passing grade during that stretch.
Giants Edge Kayvon Thibodeaux had surgery Wednesday to repair wrist fracture. HC Brian Daboll says the scaphoid bone injury leaves Thibodeaux "week-to-week," according to NFL Network's Ian Rapoport.
Colts RB Jonathan Taylor (ankle) won't practice on Wednesday, HC Shane Steichen said. That's not a good start for Taylor's chances of returning for this weekend's game vs. the Titans. We're tentatively projecting him to miss that one, again leaving the backfield to Trey Sermon and Tyler Goodson. Sermon tallied 10 carries and six targets to Goodson's five carries and three targets in the Week 5 loss to the Jaguars.
The Texans placed WR Nico Collins on IR. That knocks him out for at least the next four games vs. the Patriots, Packers, Colts, and Jets. Collins will be eligible to return for Week 10's game against the Lions. "While hamstrings can be tricky, the belief is that Nico Collins will be back sooner, rather than later," NFL Network's Ian Rapoport tweets.
Raiders WR Davante Adams (hamstring) is not expected to play vs. the Steelers this weekend, according to ESPN's Jeremy Fowler. Vegas has no reason to risk a setback with Adams' hamstring as they look to move him ahead of the November 5 trade deadline. His absence will again leave WR Jakobi Meyers, TE Brock Bowers, and WR Tre Tucker as the Raiders' top three targets. Meyers leads the team with 19 targets on a big 31.1% share over the past two weeks. Bowers has 15 targets on a 24.6% share.
Saints QB Derek Carr is expected to miss "multiple games" with the oblique injury he suffered in Monday night's loss to the Chiefs, NFL Network reports. He'll likely miss this weekend's game vs. the Bucs and the following Thursday's game against the Broncos. It sounds like he'll have a chance to be back for Week 8. New Orleans' bye isn't until Week 12.
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