The Colts made Edge Laiatu Latu the first defensive pick of the NFL Draft with the 15th selection of Round 1. Latu had to medically retire from football in the middle of his college career because of a neck injury but returned to close out a highly productive run. He racked up 33.5 tackles for loss and 23.5 sacks across two seasons at UCLA. Latu then delivered a 95th-percentile speed score at 6’5, 259 pounds at the Scouting Combine. He could compete for starter-level snaps as a rookie with the Colts but won’t be a lock for such a role. Indy sports Kwity Paye, Samson Ebukam, and Dayo Odeyingbo at the position.