The Titans have ruled DT Jeffery Simmons (ankle) out for Sunday's game against the Broncos, along with starters S Amani Hooker (shoulder), EDGE Bud Dupree (hip) and LB Zach Cunningham (elbow). Simmons is the biggest loss, both for the run defense and the pass rush. He had played through the sprain the past 2 games -- including for 81 snaps in last week's OT loss to the Chiefs. He said this week that he aggravated the ankle in that game. We'll see whether he can make it back for a Week 11 trip to Green Bay.