49ers QB Brock Purdy (shoulder) is active for tonight’s game vs. the Bills. He had a good week by all accounts, progressing to a full practice on Friday. There’s still elevated risk to using Purdy in fantasy lineups with the throwing shoulder issue, though. And the spot is tough against the Bills’ ninth-ranked QB defense in wintery Buffalo. Purdy is not a recommended QB1 play – but his return is good news for San Francisco’s skill-position players. QB Brandon Allen is inactive as the emergency third QB tonight, leaving QB Josh Dobbs as the backup.